R&D Sr. Scientist - #250489

Work Your Magic with us! Start your next chapter and join MilliporeSigma.

Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.

Your Role

Mirus Bio is expanding and has an immediate opening for a full-time R&D Senior Scientist based in Madison, WI to help develop the next generation of transfection reagents, enhancers, and related products. This role will join the R&D Chemistry Team to perform hands-on analytical development work for the next generation of transfection reagents, enhancers, and related products. This R&D Senior Scientist position reports to the Director of Chemistry.

Duties & Responsibilities

• Independently design, execute, and analyze laboratory experiments that support the development and application of new and existing transfection technologies and products. Examples of experimental design outputs include: (1) purity parameters, (2) molecular specifications, and (3) nanoscale interactions with nucleic acid of both raw materials and final product formulations.
• Provide analytical and synthetic expertise to help support, develop, perform, and transfer analytical methods for the qualification of Mirus raw materials and product formulations. This includes the characterization, purity, identity, and stability of small molecules, lipids, and polymers using various techniques, such as ultra/high performance liquid chromatography (U/HPLC), nuclear magnetic resonance spectroscopy (NMR), fourier-transform infra-red (FTIR) spectroscopy, gel permeation chromatography (GPC), mass spectrometry (MS), dynamic light scattering (DLS), and others.
• Synthesize and characterize small molecules, polymers and lipids to develop qualified materials.
• Design and perform forced degradation studies on new and existing raw materials and product formulations.
• Act as the subject matter expert (SME) to enable the technical transfer of analytical methods to internal and external partners; help write, and review SOPs related to analytical instrumentation and associated methods.
• Implement, maintain, calibrate, and, where necessary, qualify analytical instrumentation.
• Perform data analysis and interpretation to elucidate structure-property relationships and comparison of groups. For example, statistical analysis of compounds using, for example, GraphPad, t-test, ANOVA, etc.
• Stay current with scientific literature and technological advancements; provide guidance on the use and implementation of analytical techniques for various R&D projects.
• Maintain a detailed laboratory notebook and tracking of synthesized materials in a timely manner. Follow Good Documentation Practices and provide data to support process development and technology transfer.
• Attend, present data, and participate in discussions at R&D group meetings. Participate in background presentations on a rotating basis.
• Communicate effectively across multiple teams, such as Production, Quality, and Operations, to ensure alignment and eliminate barriers.
• Build positive relationships during internal and external interactions.
• Perform other duties as assigned by Director of Chemistry.
  
  

Who You Are

Minimum Qualifications:

• Doctor of Philosophy (Ph.D.) in Chemistry, Polymers, Materials or related field
• At least 1 year of analytical and synthetic chemistry experience in a corporate setting
  
  

Preferred Qualifications

• At least 3 years of analytical and synthetic chemistry experience in a corporate setting
• Experience developing, performing, maintaining, and documenting various analytical techniques in an industrial setting under GxP guidelines and regulations.
• Hands on experience in Method Development
• Ability to work independently and collaboratively in a multi-disciplinary & team-oriented environment.
• Ability to work in an organized manner, manage multiple priorities, make critical observations, and maintain records of the results.
• Proficiency with Microsoft Office including Excel, Word and PowerPoint
  
  

Travel Requirements

• Ability to travel independently up to 5%, including overnight travel
  
  

Location Requirements:

• This is an onsite role based in our Madison, WI facility.
  
  

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We celebrate all dimensions of diversity and believe that it drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of our diverse team!

If you would like to know more about what diversity, equity, and inclusion means to us, please visit https://www.emdgroup.com/en/company/press-positions.html